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AlzRisk Paper Detail
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Reference: Hassings, 2009
Cohort: Origins of Variance in the Old-Old: Octogenerian Twins
Risk Factor: Obesity


Exposure Detail
The investigators obtained the participants' self-reported weight and height measurements from surveys conducted in 1963. BMI was calculated by dividing weight in kg by height in meters squared.

Ethnicity Detail
The data came from the Swedish Twin Registry. No other information on race or ethnicity was given.

Screening and Diagnosis Detail
Screening Method:
DSM-III-R critera for "clinically definite dementia"

AD Diagnosis:
NINCDS ADRDA National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association Criteria (McKhann 1984)

Covariates & Analysis Detail
Analysis Type:
Logistic regression

Used a generalized linear mixed model (hierarchical generalized linear model)with a logit function.

AD Covariates:
Aage
Eeducation
Ggender
ALCalcohol intake
SMsmoking status

TD Covariates:
Aage
Eeducation
Ggender
ALCalcohol intake
SMsmoking status