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AlzRisk Paper Detail
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Reference: Helmer, 2003
Cohort: Personnes Agées QUID
Risk Factor: Nutritional Antioxidants


Average Follow-up Time Detail
Participants were assessed 1, 3, 5, 8 and 10 years after baseline examination. No data were reported on mean follow-up time.

Exposure Detail
Blood collection occurred at the 1-year follow-up. Samples were centrifuged and frozen in liquid nitrogen. Plasma vitamin E was quantified by reversed-phase high performance liquid chromatography

Ethnicity Detail
The study participants live in southwestern France. No other data on race or ethnicity were reported.

Screening and Diagnosis Detail
Screening Method:
Informant interview

AD Diagnosis:
DSM IIIR Diagnostic and Statistical Manual III-Revised

Total Dementia Definition: Dementia via DSM III-R.

Covariates & Analysis Detail
Analysis Type:
Logistic regression

AD Covariates:
Aage
Eeducation
Ggender
APOE4APOE e4 genotype
MMSEbaseline MMSE
BMIbody mass index
HTNhypertension
Oother
SMsmoking status
WINEwine consumption
§ Covariates for total dementia are different.

TD Covariates:
Aage
Eeducation
Ggender
APOE4APOE e4 genotype
MMSEbaseline MMSE
BMIbody mass index
HTNhypertension
SMsmoking status
WINEwine consumption

Larrieu 2004 presents identical findings in the same cohort with the same follow-up period, but with only a model adjusted for age, gender, education, and APOE e4 genotype.